RESEARCH.

专利

  • 含氨基酸的无防腐剂水溶性化妆品制造法 (10-0686884)
  • 具有女性更年期症状改善功效的功能性组成物 (10-0718559)
  • 具有皱纹改善功效的功能性组成物 (10-2008-0064680)
  • 具有抗菌效果的化妆品原料组成物 (10-2008-0064674)
  • 以蜂毒为有效成分的用于伤口治疗及烫伤治疗的治疗组成物 (10-1099550)
  • 含护肤功能性物质的无防腐剂化妆品制造方法 (10-2013-0006825)
  • 经过桑黄菇提取物的酵母发酵制作而成的功能性材料开发 (10-2014-0019574)
  • 聚谷氨酸衍生物及含有聚谷氨酸的制剂 (10-1679118)
  • 聚谷氨酸衍生物及含有聚谷氨酸的制剂 (PCT/KR2015/006220)
  • 含维生素C纳米粒子的、美白活性化妆品原料组成物 (10-2016-00063062)
  • 含维生素A纳米粒子的、改善皱纹的活性化妆品原料组成物 (10-2016-00070590
12) 含用椒井矿泉水提取的堤川黄芪,但不含防腐剂的化妆品原料组成物及其制造方法 (10-2016-0085334)
  • 不刺激肌肤的有效成分活性化 (10-2016-0109731)
  • 含桑黄菇提取物发酵物的化妆品原料组成物 (10-1677362)
  • 含精制蜂毒的无防腐剂的化妆品组政务及其制造方法 (10-2016-0161667)
  •  含维生素E纳米粒子的、改善皱纹的活性化妆品原料组成物 (10-2017-0039167)
  •  含油溶性甘草提取物纳米粒子的、美白活性化妆品原料组成物 (10-2017-0078794)
  •  藁茇根的米曲霉发酵提取物的肌肤状态改善功效化妆品原料组成物 (10-2017-0107651)
  •  包括芦苇发酵提取物的化妆品组合物 (10-2017-0138075)

研究论文

•Development of Chemiluminescence Immunoassay(CIA) and ELISA for the Detection of Anti-sperm antibodies in male sperm. Kor  J Fertil Steril. 17(1)

•Time-resolved Fluoroimmunoassay for the measurement of 17-estradiol using anti-idiotypic antibody. Korean J Animal Reprod. 16(4):325

•Chemiluminescence assay for the monitoring of phagocytic activity of HL-60 cell. J Biolum. Chmilum. 8(2):14, 1993.

•Measurement of antioxidation activity based on chmiluminescence reaction. J Biolum. Chmilum. 8(2):19, 1993.

•Studies on effect of natural drug (CP-2) extracted from the mixture of Coptis and Croton tiglium L on the immune system in tumor-induced mice. Korean Central J Medicine 58(3):177, 1993.

•Use of monoclonal antibody as a Probe for determination of milk protein denaturation. Korean J Food Sci. Resour. 14(1):12, 1994.

•Immunogenicity of murine variable and complimentarity-determining region of humanized antibodies in rabbits as an animal model. Korean J Immunology 17(1):11, 1995.

•Production of hepatitis B virus preS polypeptide in Esherishia coli by mutation of the 5′-end coding sequence and its purification and characterization. Gene 177:173, 1996.

•Development of competitive enzyme-linked immunosorbent assay for the measurement of total triiodothyronine in serum. Korean J Endocrinology 11(4):447, 1996.

•Generation and characterization of murine monoclonal antibody to hepatitis B virus preS1.  Korean J Immunology 18(3):367, 1996.

•Chemiluminescence immunoassay for measurement of estrone-3-sulfate using  monoclonal antibody to estrone-3-glucuronide. Korean J Animal Reprod. 20(2):215, 1996.

•In vitro neutralization of hepatitis B virus by monoclonal antibodiesagainst the viral surface antigen. J Med. Virol. 52(2):226, 1997.

•Construction and characterization of a single-chain immunoglobulin. J Biochem. Mol. Biol. 30(3):177, 1997.

•Generation and characterization of monoclonal antibody to human acute T lymphoblast leukemia. Korean J BRM 9(1):61, 1999.

•Mouse monoclonal antibodies to hepatitis B virus preS1 produced after immunizationrecombinant preS1 peptide.Hybridomas 19(2):185, 2000.

•Novel role of IL-6/SIL-6R signaling in the expression of inducible nitric oxide synthase(iNOS) in murine B16, metastatic melanoma clone F10.9, cells. Free Radical Biology & Medicine 42:215-227, 2007

•The process optimization for production of Phellinus linteus grown on germinated brown rice. The Korean Society for Applied Biological Chemistry. 2007

•Development of functional cosmetics using Phellinus linteus grown on germinated brown rice. The Korean Society for Applied Biological Chemistry. 2007

•Analysis for Estrogen like Activity of Astragalus membranaceus root. Korean Society for Food Engineering. 2007.

•Functional food and composition with climacteric inprovement.  Korean Society for Food Engineering. 2007.

•Stability study in various storage conditions for purified honeybee (Apis mellifera L.) venom.  The korean society of pharmacology. 29:152, 2016.

•HPLC analysis of fermented Angelicae Tenuissimae Radix. The korean society of pharmacology. 95:220, 2016.

•Anti-melanogenic and Anti-wrinkle Effects of Fermented Angelica tenuissima Extract. FASEB journal. 2017   

•Protective effect of fermented Angelica tenuissima extract on photoaging in human dermal fibroblast and keratinocyte cell lines in vitro. International Conference of the Korean Society for Molecular Celluar Biology. 2017

•Bacteriomimetic poly-γ-glutamic acid surface coating for hemocompatibility and safety of nanomaterials. Nanotoxicology 1743-5390, 2017

临床研究

  • KRIBS02的皱纹改善效果人体适用实验研究报告
  • MED-LINE Pa+++测试评价实验研究报告
  • MED-LINE BB霜防晒指数实验研究报告
  • MED-LINE防晒隔离BB粉底霜防晒指数评价实验研究报告
  • 除皱霜的皱纹改善效果人体适用实验研究报告、
  • 柔华妍真酵滋养霜使用后肌肤保护膜再生效果临床试验结果报告、
  • 肌肤斑块安全性评价人体适用实验、
  • 肌肤保护层强化改善效果人体适用实验、
  • 肌肤皱纹改善效果人体适用实验、
  • 肌肤美白改善效果人体适用实验、
  • 肌肤痘痘改善效果人体适用实验、
  • 肌肤紫外线隔离指数评价人体适用实验
(株)韩国生命科学研究所

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